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Betting the 2022 Kentucky Derby Horse Race and Odds

Scott Morris | April 30, 2022
Derby 2022 preview

The annual “Run for the Roses” will take place on Saturday, May 7, at Churchill Downs in Louisville, Kentucky. It’s the most exciting two minutes in sports and the 20-horse lineup will certainly not disappoint in 2022. Four early favorites are listed at odds of +600 or better. Here’s a look at the 2022 Kentucky Derby horses.

 

The Favorite

The overall betting favorite is the appropriately named Epicenter at +500 (pictured above). The three-year-old colt has won its last two races in a row. Epicenter captured the 1⅛-mile Risen Star back in mid-February and then won the Louisiana Derby at the end of March. Dating back to November of last year, Epicenter has won four of five starts and finished second in the other (Lecomte on Jan. 22).

 

The Top Contenders

Three horses – Messier, Taiba, and Zandon – are all listed at +600 at trusted online sportsbooks to win this year’s Kentucky Derby. Messier is the son of Belmont Stakes winner Empire Maker. Since June of last year, Messier has won or finished second in all six of his races. Most recently, he won the Santa Anita Derby Grade 2 at the beginning of April.

Taiba is the son of Gun Runner, the 2017 Horse of the Year. He won the Santa Anita Derby Grade 1 on April 9. It was just his second start. He made his debut in a maiden special at Santa Anita Park on March 5. He won by an impressive 7.5 lengths.

Zandon might be the most interesting horse in the field. He’s coming off a win in the Grade 1 Blue Grass Stakes. Trained by Chad Brown, Zandon shows maturity and tenacity that could pay off on May 7. 

 

The Longshots

Kentucky Derby 2022 betting preview

Mo Donegal

Every other horse on the board is given +800 odds or higher. The best of the bunch is Mo Donegal listed at +800 at sportsbooks. He won the Wood Memorial in his last race before the Kentucky Derby. The Wood Memorial just happens to be the exact distance – 1¼ miles – as the Derby. He’s not really a longshot at +800, but could surprise the favorites in the shorter distance race.

Smile Happy was an early favorite, but has seen his odds rise to +1200. He was cruising along with a couple first-place finishes at the end of last year, but Smile Happy has finished second in each of his last two races. The second was the Blue Grass Stakes earlier in April. He was unable to hold off Zandon in that race, which is why he now a sleeper.

The horse that many are talking about as a true longshot is Charge It. Given +2000 odds, Charge It ran second at the Florida Derby Grade 1 in what was just his third start. He’s got plenty of upside and continues to get better with each race.

The other longshot is Tiz the Bomb (+2500). Coming off a first place at the Jeff Ruby Stakes, Tiz the Bomb has the type of kick that Kentucky Derby winners have. He has yet to run his best on dirt. Tiz the Bomb will do very well in a race where the pace if fast right from the start. 

 

SBA Minutes

In this section we will post updates and notes about the current betting day/week/season. Check back daily.

Football Sharp Action Report

9/13/25

odds by SportsBetting.ag

Miami FL -17.5
Texas Tech -23.5
USC -20.5
Iowa State -21.5

MLB Sharp Action Report

9/13/25

odds by SportsBetting.ag

TEX +135

 

AP Top 25 College Football Poll

with Odds from SportsBetting.ag (Signup now for $250 in free bets)

AP TeamW/LSeason StartLive Odds
1Ohio State2-0+675+550
2Penn State2-0+700+575
3LSU2-0+1200+850
4Oregon2-0+1200+850
5Miami FL2-0+2800+2200
6Georgia2-0+650+650
7Texas1-1+600+650
8Notre Dame0-1+1000+1800
9Illinois2-0+15000+15000
10FSU2-0+3000+4500
11South Carolina2-0+6600+7500
12Clemson1-1+850+2000
13Oklahoma2-0+4000+2500
14Iowa State3-0+20000+15000
15Tennessee2-0+6600+5000
16Texas A&M2-0+3300+3300
17Ole Miss2-0+4000+4000
18S. Florida2-0+100000+20000
19Alabama1-1+900+1400
20Utah2-0+4000+5000
21Texas Tech2-0+10000+10000
22Indiana2-0+12500+10000
23Michigan1-1+3300+4000
24Auburn2-0+6000+4000
25Missouri2-0+10000+12500